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leprae. Anin silicostudy was carried out to be familiar with the molecular interactions amongst DNA gyrase and WQ compounds. WQ-3334 and WQ-3810 had been shown to have larger inhibitory exercise againstM. lepraeDNA gyrase than others. Furthermore, Examination making use of quinolone-resistantM. lepraeDNA gyrases showed that WQ-3334 experienced incr